W3School TIY Editor
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<html> <head> <script type="text/javascript"> function disableOption() { document.getElementById("pear").disabled=true } </script> </head> <body> <form> <select> <option id="apple">Apple</option> <option id="pear">Pear</option> <option id="banana">Banana</option> <option id="orange">Orange</option> </select> <input type="button" onclick="disableOption()" value="Disable pear option"> </form> </body> </html>